Efficacy Versus Placebo

Enstilar® leads to visible signs of improvement in adult plaque psoriasis, from baseline, as early as week 11

In the phase III, double-blind, randomised, vehicle-controlled PSO-FAST study:1

Enstilar effect at week 1

Adapted from Leonardi et al. J Drugs Dermatol 2015.

Study details

*Treatment success according to PGA was defined as clear or almost clear from baseline for patients with moderate/severe disease and clear from baseline for those with mild disease.1,2

Absolute reduction in mean mPASI of 2.8 at week 1 and 5.4 at week 4.1

CI: confidence interval; OR: odds ratio; PASI: psoriasis area severity index; PGA: physician’s global assessment

Some patients see noticeable improvements to the arm, back, hips and/or legs as early as week 1.1

BASELINE

CLOSE-UP

Close-up image of patient's leg at baseline

ANATOMICAL

Anatomical image of patient's leg at baseline

1 WEEK

CLOSE-UP

 Close-up image of patient's leg at week 1

ANATOMICAL

Anatomical image of patient's leg at week 1

4 WEEKS

CLOSE-UP

Close-up image of patient's leg at week 4

ANATOMICAL

Anatomical image of patient's leg at week 4

BASELINE

CLOSE-UP

Close-up image of patient's back at baseline

ANATOMICAL

Anatomical image of patient's back at baseline

1 WEEK

CLOSE-UP

Close-up image of patient's back at week 1

ANATOMICAL

Anatomical image of patient's back at week 1

4 WEEK

CLOSE-UP

Close-up image of patient's back at week 4

ANATOMICAL

Anatomical image of patient's back at week 4

BASELINE

CLOSE-UP

Close-up image of patient's hip at baseline

ANATOMICAL

Anatomical image of patient's hip at baseline

1 WEEK

CLOSE-UP

Close-up image of patient's hip at week 1

ANATOMICAL

Anatomical image of patient's hip at week 1

4 WEEK

CLOSE-UP

Close-up image of patient's hip at week 41

ANATOMICAL

Anatomical image of patient's hip at week 4

BASELINE

CLOSE-UP

Close-up image of patient's arm at baseline

ANATOMICAL