Treatment Guidance

What does the Primary Care Dermatology Society say about the treatment of plaque psoriasis in primary care?

The Primary Care Dermatology Society (PCDS) has created a treatment pathway to support GPs and GPSIs in dermatology. It states:2,3

” A combination product is often considered a first line option for chronic plaque psoriasis on the body as an effective and cosmetically acceptable therapy. 

” Many GPs and GPSIs use calcipotriol and betamethasone combination products first line… in chronic plaque psoriasis…

* This statement differs from the NICE guidelines, which state: “offer a potent corticosteroid applied once daily plus vitamin D or a vitamin D analogue applied once daily (applied separately, one in the morning and the other in the evening) for up to 4 weeks as initial treatment for adults with trunk or limb psoriasis.SIGN guidelines list short-term intermittent use of a potent topical corticosteroid or a combined potent corticosteroid plus calcipotriol ointment for rapid improvement in plaque psoriasis.5

What do primary care experts in dermatology say about the guidelines for plaque psoriasis?

Enstilar® is a combination product containing calcipotriol and betamethasone dipropionate in a foam spray formulation

As a combination product, Enstilar® tackles both aspects of psoriasis.1

Diagram showing aspects of plaque psoriasis
For illustrative purposes only. Image from a representative psoriasis patient from the PSO-FAST study (DoF LEO90100 – 003 MAR 2016)6

See how Enstilar®’s efficacy compares to its individual components
GP: General Practitioner; GPSI: General Practitioner with Special Interest; NICE: National Institute for Health and Care Excellence; SIGN: Scottish Intercollegiate Guidelines Network.
  1. McCormack PL. Drugs 2011;71(6):709–730.
  2. Primary Care Dermatology Society. Psoriasis: an overview and chronic plaque psoriasis. Available at: http://www.pcds.org.uk/clinical-guidance/psoriasis-an-overview#management. Last accessed April 2019.
  3. Primary Care Dermatology Society. Psoriasis – primary care treatment pathway. Available at: http://www.pcds.org.uk/ee/images/uploads/general/Psoriasis_algorithm-web-1.pdf. Last accessed April 2019.
  4. National Institute for Health and Care Excellence (NICE). Psoriasis: assessment and management. Clinical guideline (CG)153. Available at: https://www.nice.org.uk/guidance/cg153/resources/psoriasis-assessment-and-management-pdf-35109629621701. Last accessed April 2019.
  5. Scottish Intercollegiate Guidelines Network (SIGN). Diagnosis and management of psoriasis and psoriatic arthritis in adults Available at: https://www.sign.ac.uk/assets/sign121.pdf. Last accessed April 2019.
  6. Data on File: LEO90100 – 003 MAR 2016.
MAT-25297 August 2019

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MAT-29941 November 2019

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